• Custom TAL Effector Nucleases (TALEN) Service

    Comparison of the Three Genome Editing Tools


    Vigene TALEN Design Process


    TALEN in Action

    Two (Left & Right) AAVS1-C TALEN were created using ViGene's Custom TALEN Design (Fig. A) and transfected into HEK293T cells for functional validation (Fig.D). AAVS1-TALEN was then sequenced to confirm for TALEN cut outcome (Fig. B & C).

    Result: 15 clones were sequenced, 9 contains deletions with 8 being different deletions , results in 8 mutations created by the TALEN design.