• Publications

    Vigene products and services have been used worldwide by scientists in academia and industry. Below is a selection of recently cited publcations showcasing our products and services.




    ORF Collection and Shuttle Vectors



    Yin, C. et al. In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models. Mol Ther. 25, 1168-1186 (2017). DOI: 10.1016/j.ymthe.2017.03.012.

    Zakas, P.M. et al. Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction.Nat Biotechnolo. 35, 35-37 (2017). DOI: 10.1038/nbt.3677.

    Zing B. et al. AAV-Mediated Anterograde Transsynaptic Tagging: Mapping Corticocollicular Input-Defined Neural Pathways for Defense Behaviors. Neuron 93, 33-47 (2017). DOI: 10.1016/j.neuron.2016.11.045.

    Yang, J. et al. Coupling optogenetic stimulation with NanoLuc-based luminescence (BRET) Ca++ sensing.Nat Commun. 25, 13268 (2016). DOI: 10.1038/ncomms13268.

    Zhao, X. et al. Caspase-2 cleavage of tau reversibly impairs memory. Nat. Med. 22, 1268-1276 (2016). DOI: 10.1038/nm.4199.

    Schober, A.L. et al. Recombinant Adeno-Associated Virus Serotype 6 (rAAV6) Potently and Preferentially Transduces Rat Astrocytes In vitro and In vivo. Front Cell Neurosci. 10, 262 (2016). DOI: 10.1016/j.ymthe.2017.03.012.


    Zhang, L.et al. Anti-inflammatory effects of Lefty-1n in renal tubulointerstitial inflammation via regulation of NF-kB pathway. International Journal of Molecular Medicine 41, 1293-1304 (2018). DOI: 10.3892/ijmm.2017.3327

    Li, H.et al. p38 MAPKMK2 pathway reglates the heat stress induced accumulation of reactive oxygen species that mediates apoptotic cell death in glial cells. Oncology Letters 15, 775-782 (2018). DOI: 10.3892/ol.2017.7360.

    Sun, J.-X.et al. SNAI1, an endothelial–mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.Angiogenesis, 1-18 (2018). DOI: 10.1007/s10456-018-9614-9

    Song, X.et al. Temozolomide–perillyl alcohol conjugate downregulates O6 -methylguanin DNA methltransferase via inducing ubiquitination-dependent proteolysis in non-small cell lung cancer. Cell Death & Disease, 9, 202 (2018). DOI: 10.1038/s41419-017-0193-2


    Xie, H.et al. MEIS-1 level in unresectable hepatocellular carcinoma can predict the post-treatment outcomes of radiofrequency ablation. Oncotarget, 9, 15252-15265 (2018). DOI: 10.18632/oncotarget.24165

    Li, Y.et al. MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells. BMC Cancer, 18, 404 (2018). DOI: 10.1186/s12885-018-4233-9

    Mostafa, A.et al. S-phase Specific Downregulation of Human O6-Methylguanine DNA Methyltransferase (MGMT) and its Serendipitous Interactions with PCNA and p21cip1 Proteins in Glioma Cells. Neoplasia, 20, 305-323 (2018). DOI: 10.1016/j.neo.2018.01.010

    ORF Collection and Shuttle Vectors

    Bao, X.et al. Capturing the interactome of newly transcribed RNA. Nature Methods, 15, 213-220 (2018). DOI: 10.1038/nmeth.4595

    Paredes, F.et al. Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer. PNAS, 201720693 (2018). DOI:10.1073/pnas.1720693115

    Liu, F.et al. Cleavage of potassium channel Kv2.1 by BACE2 reduces neuronal apoptosis. Molecular Psychiatry, 1 (2018). DOI: 10.1038/s41380-018-0060-2

    Zhang, J. et al. Loss of Lysyl Oxidase-like 3 Attenuates Embryonic Lung Development in Mice. Sci. Rep. 6, (2016). DOI: 10.1038/srep33856.

    Tao, L. et al. Frizzled proteins are colonic epithelial receptors for C. difficile toxin B. Nature 538, 350-355 (2016). DOI: 10.1038/nature19799

    Chung, I.-C. et al. Pyk2 activates the NLRP3 inflammasome by directly phosphorylating ASC and contributes to inflammasome-dependent peritonitis. Sci Rep. 6, 36214 (2016). DOI: 10.1038/srep36214.

    Ying, T.-H. et al. Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells. Sci Rep. 6, 29385 (2016). DOI: 10.1038/srep29385.


    Liu, L.et al. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front. Mol. Neurosci. 11 (2018). DOI: 10.3389/fnmol.2018.00076

    Li, H.et al. Brg1 promotes liver fibrosis via activation of hepatic stellate cells. Experimental Cell Research 364, 191-197 (2018). DOI: 10.1016/j.yexcr.2018.02.003

    Luo, J.et al. HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3. Cancer Sci. 109, 317-329 (2018). DOI: 10.1111/cas.13453

    Hu, H.et al. Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3. Molecular Cancer 17, 18 (2018). DOI: 10.1186/s12943-018-0761-9